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A subsequent study by Derossi et al

Recent availability of genome-wide association studies (GWAS) has identified several new genetic loci, including a gene desert region on chromosome 8q24 (36)

The consistency of these signals across analytical and computational approachesincluding differential statistics, pathway analysis, and ML-based feature selectionas well as across complementary metabolomics platforms, supports the robustness of the identified signatures and reduces the likelihood of platform or method-specific effects

These may be contraindications

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